Which statement best describes Schedule II controlled substances?

• A. They have the highest potential for abuse
• B. They have the lowest potential for abuse
• C. They have no medical use
• D. They are not regulated

Answer: (A)

Abuse potential and medical use drive how drugs are scheduled. Schedule II substances have a high potential for abuse but do have accepted medical uses, and they are subject to strict regulation (prescriptions, limited refills, careful recordkeeping). That combination is why the statement describing them as having a high potential for abuse is the best fit among the options: it captures their strong abuse risk while acknowledging they’re used medically. The other statements don’t fit: they do have medical use, they are regulated, and they are not the lowest in abuse potential.